Crème M.E.C.
A lightweight, mattifying moisturizer that purifies and helps regulate excess oil.
“I love this for anyone struggling with excess oil it keeps the skin matte and balanced without ever feeling stripped.” —Sarah Akram
- Regular price
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$225.00 - Regular price
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- Sale price
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$225.00
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Biologique Recherche’s Crème M.E.C. has been clinically proven to improve skin remodeling by +25%* and enhance plumpness by +22%*, in just 56 days—restoring density, refining contours harmony, and renewing skin with lasting suppleness and light-reflecting vitality.
*Clinical scoring performed under dermatological supervision. Tested on a mixed panel of 65 subjects aged 40 to 63 years, phototypes I to IV. Twice-daily application of the product for 56 days.
Your skin’s youthful appearance relies on the Extra-Cellular Matrix, the underlying system that maintains skin firmness, suppleness, hydration, and tensile strength.
Over time the Extra-Cellular Matrix's essential components—collagen, elastin, glycosaminoglycans, and glycoproteins—begin to weaken, and skin loses density, definition softens, and fine lines appear.
Crème M.E.C. supports the optimal harmony of the Extra-Cellular Matrix, addressing visible signs of aging where they originate.
WHO IT'S FOR
How To Use
About Biologique Recherche
French Skincare Without Compromise
Founded in the late 1970s by biologist Yvan Allouche and physiotherapist Josette Allouche, Biologique Recherche pioneered a clinical, skin-first approach to skincare. Its potent formulas and treatment protocols are designed to treat the skin exactly as it presents, with routines tailored to each person's needs.
Discover icons like Lotion P50, Masque VIP O2 and La Grande Creme, and experience the methodology that made Biologique Recherche a cult favorite among skincare professionals.
The Science
A CLINICAL, SKIN-FIRST METHODOLOGY
Biologique Recherche formulas are built around potent active ingredients and a methodical approach: assess the skin as it is today, then treat exactly what it needs. Routines are personalized rather than one-size-fits-all, and products are layered in a precise order.
THE ROLE OF LOTION P50
Lotion P50, the brand's signature exfoliating lotion, is the foundation of most routines. It refines texture, helps balance the skin and prepares it so the serums, masks and creams that follow can work more effectively.
Full Ingredient List




Why Clients Love It
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Key Benefits
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Visible Results
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A Formula We Love

French Skincare Without Compromise
Founded in the late 1970s by biologist Yvan Allouche and physiotherapist Josette Allouche, Biologique Recherche treats the skin exactly as it presents, with potent formulas and personalized protocols trusted by skincare professionals around the world.
“Biologique Recherche is the foundation of so many of my clients' routines. It is precise, results-driven skincare, and when it is matched to the right skin, the transformation is remarkable.” - Sarah Akram
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